Publications
Publications
Publications
Publications
Switching Metazoan Fatty Acid Synthase Between Reducing and Nonreducing Elongation Mode via Programming of the Ketoreductase Domain
Engineering metazoan fatty acid synthase to control chain length applied in yeast
Ludig D., Zhai X., Rittner A., Gusenda C., Heinz M., Berlage S., Gao N., Jervis A., Zhou Y., Grininger M.
Nature Chemical Biology
January 2026
Design eines aus der Fettsäuresynthase der Maus abgeleiteten Multienzyms für die kompartimentierte chemo‐enzymatische Synthese von 2‐Pyron‐Polyketiden
Lehmann F., Joachim N., Parthun C., Grininger M.
Angewandte Chemie
November 2025
Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides
Lehmann F., Joachim N., Parthun C., Grininger M.
Angewandte Chemie International Edition
November 2025
Molecular mechanisms of the mammalian fatty acid cycle
Gusenda C., Grininger M.
Trends in Biochemical Sciences
November 2025
The enzyme kinetics of branched‐chain fatty acid synthesis of metazoan fatty acid synthase
Gusenda C., Ochs K., Cui Z., Ludig D., Grininger M.
Protein Science
July 2025
Design principles imprinted by evolution
Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases
Gusenda C., Berlage S., Burkhart I., Chagot B., Weissman K., Schwalbe H., Grininger M.
STAR Protocols
April 2025
Die Kinetik der Kohlenstoff‐Kohlenstoff‐Bindungsbildung in der metazoischen Fettsäure Synthase und ihr Einfluss auf die Produktgenauigkeit
Gusenda C., Calixto A., Da Silva J., Fernandes P., Grininger M.
Angewandte Chemie
November 2024
The Kinetics of Carbon‐Carbon Bond Formation in Metazoan Fatty Acid Synthase and Its Impact on Product Fidelity
Gusenda C., Calixto A., Da Silva J., Fernandes P., Grininger M.
Angewandte Chemie International Edition
November 2024